Sharab A

Journals now require that Methods declare RRIDs for antibodies, authentication for cell lines, and animal-rigor reporting. Methods Verifier is the pre-submission check: paste your Methods + Key-Resources and get a per-resource verdict — PASS / FAIL / NEEDS-VERIFICATION — each cited to a public record. Claude does the two jobs a lookup can't. It extracts a typed resource inventory out of messy, hyphen-stripped prose, and it reasons about whether each antibody was validated with a genetic knockout control — the specificity gold standard. Deterministic gates then issue every identity verdict against ground truth a model cannot fabricate: cell lines against the ICLAC register, antibodies against the Antibody Registry, software against SciCrunch RRIDs. A missing datum → it abstains, cited. Every finding is tagged registry (deterministic) or model judgment (Claude), so the two are never blurred. Why it must exist: over the entire 594-line ICLAC register, a frontier model names a contaminated line from memory only 18% of the time — confidently wrong on 230. Give it the register and extraction catches 92%; on 47 real open-access papers, 89% with 0 false alarms on 14 clean controls, every FAIL cited to an ICLAC ID + CVCL.

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