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CuraVar is a "show your work" assistant for classifying genetic variants. Claude reads the evidence and proposes which ACMG/AMP rules apply — each with a citation — then deterministic code does the final scoring, so the AI never touches the number and the same evidence always gives the same answer. Every step is written to a tamper-proof, hash-chained ledger that can be re-verified on demand. Built for the Built with Claude: Life Sciences hackathon. Research decision-support only — the final call stays with a qualified professional.

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hunain_arif

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