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OncologyOS helps cancer patients find the right clinical trials, using just their discharge documents The problem. Every year roughly 2 million Americans (and ~20 million people worldwide) are diagnosed with cancer, and almost overnight each one is handed a life-or-death information problem they're not equipped to solve. The relevant knowledge is real but scattered and unreadable: ~19,000 cancer clinical trials are actively recruiting in the U.S. alone, alongside thousands of approved drugs, off-label and repurposing options, and dense genomic and pathology reports — yet fewer than 1 in 20 adult cancer patients ever enrolls in a trial, and the most common reason isn't ineligibility, it's that neither the patient nor their busy oncologist ever finds the right one. Matching a single patient to the right options means cross-referencing their diagnosis, stage, biomarkers, prior therapies, and comorbidities against eligibility fine print written for specialists — work that is slow, expensive, and largely manual, so it mostly doesn't happen. The result is a brutal asymmetry: the options that could extend or save a life often exist, but the patient never learns they're there.

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