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EpiSim transforms research papers into interactive simulators. Upload a PDF or paste an arxiv ID — a six-agent pipeline extracts the mathematical model (ODEs, parameters, initial conditions), generates a Streamlit simulator with parameter sliders, validates output against the paper's results, and produces a downloadable Python script. Opus 4.6 features: adaptive thinking at per-agent effort levels (Reader at max, Summarizer at medium, Builder at high — five agents, three effort levels). Real-time visible thinking streams into a typewriter console. 1M context window holds entire papers with zero RAG. 128K output generates complete apps in one API call. Parallel multi-agent execution via ThreadPoolExecutor (~40% faster) Tested across domains: COVID-19 (SIDARTHE, 8 compartments), Dengue, Ebola, and Ecology (Lotka-Volterra). The pipeline reads differential equations, not just epidemiology. 76 tests passing.

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