# peptides that don't work

- **Event:** [GPT-6 Astra Hackathon SF](https://cerebralvalley.ai/e/openai-gpt-6-astra-sf)
- **When:** Tue, Sep 8 at 9:00 AM – 10:00 PM (PDT)
- **Where:** San Francisco, CA
- **Team:** [Armin Foroughi](https://cerebralvalley.ai/u/arms)
- **GitHub:** https://github.com/arminforoughi/steering-bench
- **Demo video:** https://youtu.be/1xOOLF7WMP4?is=MLF7_S7ulFVuY8tK
- **Gallery:** https://cerebralvalley.ai/e/openai-gpt-6-astra-sf/hackathon/gallery
- **Page:** https://cerebralvalley.ai/e/openai-gpt-6-astra-sf/hackathon/gallery/63

simulating peptide changes, and what compounds will not work with the bounding pockets.


The bench loads a protein structure, finds the pockets on its surface, and proposes peptides that should fit: designing new ones, and searching 17,000 real catalogued ones, scored on the same objective so you can see which wins. You drive it in plain English — one question, and GPT-6 Astra calls the tools, runs the physics, and pulls trial results for drugs already approved against that target.

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