# Alzheimer Voice

- **Event:** [Built with Opus 4.6: a Claude Code hackathon](https://cerebralvalley.ai/e/claude-code-hackathon)
- **When:** Feb 10 at 12:00 PM – Feb 17 at 10:00 AM (EST)
- **Where:** Location TBA
- **Team:** [Remi FRANCOIS](https://cerebralvalley.ai/u/remifran)
- **GitHub:** https://github.com/remifrancois/alzheimervoice
- **Demo video:** https://youtu.be/F61TxC3r7U0
- **Gallery:** https://cerebralvalley.ai/e/claude-code-hackathon/hackathon/gallery
- **Page:** https://cerebralvalley.ai/e/claude-code-hackathon/hackathon/gallery/162

alzheimervoice is the world's first open-source cognitive voice fingerprint engine that detects early signs of Alzheimer's, Parkinson's, depression, Lewy Body Dementia, and Frontotemporal Dementia through voice analysis alone. A 5-minute daily conversation is all it takes. The V5 engine extracts 107 biomarkers from natural speech across 11 cognitive domains. We sourced, transcribed, and ingested 80+ research papers to train the engine — making it uniquely evidence-grounded. Key innovations:
- Opus 4.6 dual-pass extraction with Extended Thinking — self-correction against 25 deterministic NLP anchors reduces variability by 40-50%
- 35-rule differential diagnosis across 11 conditions — the only tool performing linguistic differential diagnosis
- Topic-aware scoring eliminates false positives
- Weekly deep analysis with 32K Extended Thinking
The engine powers alzheimervoice.org for demo

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