# Team Veritas

- **Event:** [Built with Claude: Life Sciences](https://cerebralvalley.ai/e/built-with-claude-life-sciences)
- **When:** Jul 7 at 12:00 PM – Jul 14 at 12:00 AM (EDT)
- **Where:** Online
- **Team:** [Sreenath Menon](https://cerebralvalley.ai/u/sreenath)
- **GitHub:** https://github.com/sreenathmmenon/veritas/
- **Demo video:** https://youtu.be/HqZ-j2XyP6Q
- **Gallery:** https://cerebralvalley.ai/e/built-with-claude-life-sciences/hackathon/gallery
- **Page:** https://cerebralvalley.ai/e/built-with-claude-life-sciences/hackathon/gallery/183

VERITAS is an independent verifier for AI-generated single-cell findings. A copilot says "gene X is up in Alzheimer's." VERITAS re-runs that claim across every defensible analysis choice the analyst didn't try, checks the experimental design for structural confounds, and returns a signed verdict: SURVIVES, DOES NOT SURVIVE, or UNVERIFIABLE. Every flag carries a re-derivable statistic, never a model opinion.

The methods are real, not heuristics: donor-level DESeq2 pseudobulk, design-matrix batch models, Leiden, Harmony, Scrublet. Where a real method wasn't possible (ambient contamination needs empty-droplet data we never receive), we deleted the check rather than ship a proxy.

What we found: pointing VERITAS at real published Alzheimer's cortex data exposed a false-green in VERITAS itself. A finding that broke only at the pseudobulk axis still scored 0.94 and was certified GREEN — the exact failure the tool exists to catch. We made pseudobulk a critical axis and wrote it up.

Why it matters: Mathys et al. 2019 reported 14,274 Alzheimer's DEGs computed at the cell level. A donor-level reanalysis (eLife 2023) found 26. AI now generates findings faster than anyone can check them. Claude Science ships a reviewer, but it's the same model checking itself. VERITAS is the independent check: it re-runs the analysis and computes the number.

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